By Florian Schütt MD, Frank G. Holz MD (auth.), Winfried E. Alberti MD, Gisbert Richard MD, Robert H. Sagerman MD, FACR (eds.)
Age-related macular degeneration (ARMD) is a common affliction of the aged and the most typical reason for blindness. up to now decade quite a few healing innovations were constructed and made on hand for scientific use. learn effects are maturing, yet so far the reader has needed to trawl the numerous journals of ophthalmology and radiotherapy to procure correct info. This ebook is designed to rectify this case via delivering a entire file at the present sorts of therapy for ARMD. After an introductory part at the prognosis and lines of ARMD, person chapters written by way of across the world famous specialists record intimately the clinical basics of radiotherapy and ophthalmic surgical procedure, the remedy recommendations, strength side-effects, and final result. numerous overseas examine teams file the result of medical learn, focussing at the effectiveness of either radiotherapy and surgical procedure. distinctive radiotherapy techiques reminiscent of proton beam remedy and brachytherapy are defined, and their benefits and downsides mentioned. This detailed e-book may be of giant worth to all with curiosity in ARMD.
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Extra info for Age-Related Macular Degeneration: Current Treatment Concepts
FUJII, and EUGENE DE JUAN JR. -G. 1 Introduction Age-related macular degeneration (ARMD) is the leading cause of blindness and a maj or public health problem in many developed countries, particularly in Europe and North America (HAWKINS et al. 1999; KRUMPASZKY et al. 1999; KLEIN et al. 1992; LEIBOWITZ et al. 1980). neovascular complications of ARMD account for 80%-90% of cases of blindness from this disease, while atrophic changes are responsible for the remainder. Despite intensive research efforts worldwide to combat the disease, no treatment is currently available for the non-neovascular variety, while only limited therapy can be offered to patients with the neovascular form.
The proposed treatment was not pursued for some time until MACHEMER and STEINHORST (1 993b ) finally demonstrated its feasibility in humans. Their technique involves lensectomy, complete vitrectomy, planned retinal detachment by transscleral infusion of fluid under the retina, 360° peripheral circumferential retinotomy, rotation of the retina around the optic disc, and retinal reattachment with silicone oil tamponade. A number of modifications have since been made to this technique by several investigators, but many still require large (NINoMIYA et al.
Richard 24 -- . ~ --.. -. ~ . -- - ~ _. ~ . - .. ~- ~ - . -:: .. • oc ~..! :. ~ . ~~- • -_ • Fig, 3,6. Normal OCT. The horizontal red line represents the highly reflective pigment epithelium and the overlying yellow layer the sensory retina. The foveolar depression is visible. ,,~--· ~ ~~~~~-:- - " . - --- Fig. 7. a Soft drusen on funduscopy. Biomicroscopy of soft drusen show yellow-white lesions which are ill-defined. b Soft drusen, OCT. As soft drusen are almost nonreflective, they present here as small focal detachments of the RPE.
Age-Related Macular Degeneration: Current Treatment Concepts by Florian Schütt MD, Frank G. Holz MD (auth.), Winfried E. Alberti MD, Gisbert Richard MD, Robert H. Sagerman MD, FACR (eds.)